Argentina have World Cup qualifiers with Paraguay and Peru next month but Aguero has been ruled out for just under a month.
The news will irk City, though Argentina may understandably wish to verify whether the player can at least play some part in their crucial qualifiers.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.