Leo Messi scored a sublime free kick to wrap up the win and leave Paraguay in real danger of missing out on qualification.
Ecuador beat Bolivia 1-0 to move second in qualifying, whilst Uruguay were stunned by a 4-0 defeat to Colombia.
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Who of Europe’s top strikers will move to England this summer?
After a dreadful start to their Bundesliga campaign, Borussia Dortmund appear to have weathered the storm after going five matches without defeat.