Bastian Schweinsteiger is suspended for the game after picking up a yellow card in a win over the same opponents on Friday.
And Julian Draxler, the Schalke playmaker, suffered concussion in the game, leaving Jogi Low short in midfield.
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Liverpool have unveiled their new home kit for next season, sticking with the hugely popular retro styling of the current shirt.
The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.