The Premier League club are closing in on the signing of the Uruguayan.
According to Il Resto del Carlino Ramirez will be allowed to leave for 15 million euros paid in two installments.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.