The 22-year-old midfielder has been out of action since August with a back problem.
Dortmund’s sporting director, Michael Zorc, has revealed that the midfielder’s condition is not improving.
“He is not making any progress at the moment,” Zorc told Zeitung. “We do not know when he will be able to play again.”
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.