Messi’s goals against Rayo Vallecano at the weekend means it is only Celta left for the record to be set.
Cristiano Ronaldo achieved the same feat last season but scored fewer goals than Messi is on course for – the Argentine has already netted 42 times in the league.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.