Elsewhere, Napoli lost 2-0 to Viktoria Plzen to go out 5-0 on aggregate, Lazio won by the same score against Borussia Moenchengladbach to secure their progress, and Zenit St Petersburg survived a Liverpool fightback to go through on away goals.
Bordeaux knocked out Dynamo Kiev, Newcastle overcame Metalist Kharkiv, Anzhi Makhachkala beat Hannover and Benfica knocked out Bayer Leverkusen.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.