The Chelsea left back has been ruled out through injury from games against Moldova and possibly Ukraine too.
Boss Roy Hodgson is still hopeful he could be fit for the Ukraine game.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.