Van Persie signed from Arsenal in the summer, and last season’s top scorer can make a difference, Giggs believes.
“We lost it on goal difference, so hopefully the goals that he’s bringing, if it does come down to goal difference, then we’ll have the upper hand this time,” the Welshman told Sky Sports News.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.