The Andalucians could be joined in the Champions League group stage by Udinese, who drew 1-1 with Braga in Portugal.
Hapoel Kiryat Shmona were beaten 2-0 by BATE, while Maribor lost 2-1 at Dinamo Zagreb and Limassol beat Anderlecht by the same score at home.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.