Mali fought back to draw 1-1 against the hosts in the quarter finals for the second year in a row.
They will now face the Ivory Coast or Nigeria in the semi finals later this week.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.