United boss Sir Alex Ferguson has named a number of youngster in their 21-man squad for the clashw ith the Romanian side on Tuesday.
Antonio Valencia and Ashley Young will not feature for United due to injuries.
Man Utd squad: De Gea, Lindegaard; Buttner, Evans, Evra, Ferdinand, M.Keane, Rafael, Wootton; Anderson, Cleverley, Fletcher, Lingard, Nani, Powell, Tunnicliffe; Hernandez, Kagawa, Rooney, van Persie, Welbeck.
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Since Guus Hiddink arrived at the helm, Chelsea have improved considerably after a tricky start to the campaign.
Newcastle United are staring down the barrel of relegation to the Championship for the second time in the past eight years.