Kagawa missed Japan’s World Cup qualifier against Iraq because he felt a twinge in his lower back during training ahead of the match.
Japan coach Alberto Zaccheroni decided not to risk the 23-year-old playmaker.
The injury could see the highly-rated midfielder miss United’s home game against Wigan on Saturday.
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The start of the 2017-18 Premier League season is just around the corner and is shaping up to be one of the most competitive yet.
As always it is the so called “big clubs” that have splashed the most cash in the transfer window so far this summer. Manchester United or City? Arsenal or Tottenham? Who are the winners and losers of the transfer window so far?