The club are being heavily linked on Thursday morning with a big money move for the Sevilla striker.
If City sign Negredo, he will join former team mate Jesus Navas, who also left Seville for Manchester this summer.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.