The club’s convincing lead was achieved after a superb first leg performance in the last 16 tie, but their coach is taking nothing for granted.
“We are going to have to play better in Barcelona than we did at home,” Milan boss Massimiliano Allegri conceded.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.