Goals from Kevin Prince Boateng and Sulley Muntari give the Italian side a commanding first leg lead.
Barcelona must now find a way to win by at least two clear goals without conceding to progress.
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Summer 2016 is set to be a very exciting time for football fans, as this is when the long awaited Euro 2016 tournament kicks off.
Since Guus Hiddink arrived at the helm, Chelsea have improved considerably after a tricky start to the campaign.