The 35-year-old, who has not featured for Reading since December, needs surgery to resolve a his hip injury.
He Tweeted: “Rehabilitation has not been successful. [It] seems at this point surgery is our only option meaning my season is over.
“Everything that could have been done has been done.”
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Since Guus Hiddink arrived at the helm, Chelsea have improved considerably after a tricky start to the campaign.
Newcastle United are staring down the barrel of relegation to the Championship for the second time in the past eight years.