Reports have recently linked with the 21-year-old with the likes of Manchester United and Arsenal.
Niguez has reportedly also rejected an improved contract offer from Atletico Madrid.
When asked about bids for the young midfielder Simeone said: “That depends on the club. Our interest in is trying to make players the best they can be.
“I think it would be premature for Saul to leave because he’s young and to continue growing as a player there is nowhere better than his home – Atletico.”
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The start of the 2017-18 Premier League season is just around the corner and is shaping up to be one of the most competitive yet.
As always it is the so called “big clubs” that have splashed the most cash in the transfer window so far this summer. Manchester United or City? Arsenal or Tottenham? Who are the winners and losers of the transfer window so far?