The two sides came out at the Centenario Stadium in Resistencia but not for long.
The first leg in Brazil was won 2-1 by the home team thanks to a late Neymar penalty.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.