United overtook Chelsea, who drew 1-1 with Swansea, to go top for the first time this season.
Manchester City also failed to win, drawing 0-0 with West Ham, while Tottenham were beaten 1-0 by Wigan.
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Who of Europe’s top strikers will move to England this summer?
After a dreadful start to their Bundesliga campaign, Borussia Dortmund appear to have weathered the storm after going five matches without defeat.