Vilanova was in New York and set to return this weekend to Catalonia to witness Barcelona take on Valencia.
However he has chosen on medical advice to stay in the US, claim Sport, as he focuses on being able to return to the dugout for the end of the season.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.