Vilanova missed much of last season after being appointed to replace Pep Guardiola because of throat cancer.
“Following routine tests, it was decided that he would follow a course of treatment to continue to control his illness that is incompatible with fulfilling his role as coach of the first team,” club President Sandro Rosell said.
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Who of Europe’s top strikers will move to England this summer?
After a dreadful start to their Bundesliga campaign, Borussia Dortmund appear to have weathered the storm after going five matches without defeat.