Club President Sandro Rosell will be travelling to New York, where Vilanova is undergoing treatment for cancer, to determine whether he can return or not for the Milan game.
Barcelona are 2-0 down following the first leg in Italy earlier this month.
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Summer 2016 is set to be a very exciting time for football fans, as this is when the long awaited Euro 2016 tournament kicks off.
Since Guus Hiddink arrived at the helm, Chelsea have improved considerably after a tricky start to the campaign.