PSV face Ajax on Sunday in a battle of the top two but Vitesse missed the chance to put the pressure on both with their draw.
There will be four rounds of games left after this weekend with Ajax after their third title.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.