Wilshere will play his first game for 14 months in an under 21 Premier League game against West Brom on Monday.
He will play an hour of the match, with Arsene Wenger hoping he can be considered for a return after the international break.
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The reputation of the Premier League means it is the most popular and one of the most watched leagues in the world.
Five English clubs will compete in the last sixteen of the Champions League for the first time ever as Liverpool, Manchester United, Manchester City, Chelsea and Tottenham face some difficult away matches.