The Sunday Mirror says the Russian is set to end his stay at White Hart Lane in January.
Pavlyuchenko is behind Robbie Keane, Jermain Defoe and Peter Crouch in the pecking order at Spurs.
The 27-year-old is desperate to get regular first-team football in order to feature for Russia in the World Cup finals in South Africa next year, should they reach it.
Valencia are ready to offer the striker first-team football.
