Lukas Podolski scored twice, with Theo Walcott and Aaron Ramsey netting the other goals for the Gunners as they move above Tottenham with one game remaining this season.
For their visitors, Wigan, who had won the FA Cup on Saturday and scored through Shaun Maloney, the defeat brought to an end a hugely impressive eight year stint in the Premier League.
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Who of Europe’s top strikers will move to England this summer?
After a dreadful start to their Bundesliga campaign, Borussia Dortmund appear to have weathered the storm after going five matches without defeat.