Spain boss Vicente del Bosque has named a strong squad for the clash with the Three Lions on Saturday.
“Spain are a great team with so many great players. So the experience of taking them on at Wembley will be fantastic for us,” Lampard told The Sun.
“It will be a terrific test against such a quality side and such brilliant individuals.
“But if we can put in a top performance – as I’m sure we can – it can give us a real boost for what’s in store at the European Championship finals next summer.”
Lampard did not feature in the starting XI for the 2-2 draw with Montenegro last month.
He stressed: “England will always matter so much to me. I love playing for my country, I always have done.
“It’s always a very proud moment and I will always feel honoured to be a part of the England squad. If it didn’t matter it wouldn’t be worth turning up.
“It doesn’t matter if I’m on the bench or in the squad. I will always be there if selected.”
