The 24-year-old has recently been linked with several top European clubs, including Manchester United.
The highly-rated Uruguayan striker recently signed a new contract that will keep him at Napoli until the summer of 2016.
“I should have my license as president of Napoli taken away if I sell Cavani unless it is for 100 million euros,” De Laurentiis told Corriere dello Sport.
“He recently signed a contract extension and I have given him a good deal, which he merits.”
