Vilanova had to leave the post after suffering a relapse in his battle against throat cancer.
Iniesta told AS: “Tito will once again win this terrible battle facing him. On behalf of the players and everyone, I send him all my love and support. At the end of the day, this is about a person, not a coach.”
Meanwhile Messi took to Facebook to issue a simple statement, saying: “Strength Tito! We are all with you in this fight!”
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Since Guus Hiddink arrived at the helm, Chelsea have improved considerably after a tricky start to the campaign.
Newcastle United are staring down the barrel of relegation to the Championship for the second time in the past eight years.