The Mexico international picke dup the ankle injury in PSV’s 2-1 win over Manchester United last week.
“Andres Guardado will be sidelined for four to six weeks after sustaining an ankle injury,” PSV announced on their website.
“Guardado underwent an MRI scan in hospital on Monday afternoon.
“Last week, the ankle was still too swollen but a second scan has determined the Mexican will be out of action for four to six weeks.”
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The Portuguese legend has headed home from the World Cup in Russia but there is no doubt he made his mark.
Liverpool have unveiled their new home kit for next season, sticking with the hugely popular retro styling of the current shirt.