The first leg of their last-16 encounter ended in a 2-1 win to Inter Milan.
“For us, this match is like the final of the Champions League,” the Argentina international told Sky Sports.
“Inter will not play ultra-defensive, though, at Stamford Bridge. That would be a mistake because to offer Chelsea the ball is to practically kiss goodbye to our future in Europe.
“The pressure is on Chelsea because they need goals and they will have to take risks at home.”
“I think it will be a very hard and intense match at Stamford Bridge, but that is normal,” he added.
“In the San Siro we showed what we can do and now we have to find that level again.
“To stop men like Drogba will not be easy, but in training we have worked hard on that and on Chelsea’s other key men.
“If Chelsea want to reach the quarter-finals of the Champions League they will need to be at 150 per cent because Inter have no intention of giving them any hope.”