Manchester United boss Ruben Amorim has confirmed his side will be without three key players for Sunday’s clash with Manchester City.
Matheus Cunha, Mason Mount and Diogo Dalot have all been ruled out after picking up injuries before and during the international break.
Cunha suffered a hamstring problem in the win over Burnley, Mount was withdrawn at half-time of the same game, and Dalot pulled out of Portugal duty with muscle discomfort.
The trio have been ever-present for United this season, making their absences a major concern ahead of the first Manchester derby of the campaign.
Amorim will be forced into changes, with new signing Senne Lammens set for his first squad appearance, though the goalkeeper will not start at the Etihad.