The first match ended in a goalless draw.
Totti said: “The qualification is still open. I think a goalless draw is a good result and I think in Lyon, we can land a punch.
“The French team is very good, but I think in this game, we were able to handle the difficult situations we faced.”
Totti added: “Ever since I started playing football, my main aim has been to win the Champions League.
“I’ve won the Scudetto, and I’ve won the World Cup, but I’m missing the Champions League, the Coppa Italia and finishing as the top scorer in Serie A.”