Tevez submitted a transfer request in December, but decided to perform a U-turn following clear-the-air talks with the club’s owner.
But the Argentina international is now desperate to leave Eastlands again to be close to his family.
“It is with great regret that I have to inform Manchester City of my wish to leave the club,” he said in a statement.
“I would like to state that I have great respect for the club, its supporters and the owner, Sheikh Mansour, who has been nothing other than respectful to me.
“I hope that the people understand the difficult circumstances I have been living under the past 12 months, in regards to my family.
“Living without my children in Manchester has been incredibly challenging for me.
“Everything I do, I do for my daughters, Katie and Florencia. I need to be closer to them and to spend more time with them.
“I need them to be happy because my life is about them now. I need to be in a place where they can adapt.
“Being captain of Manchester City, qualifying for the Champions League, winning the FA Cup and finishing as top-scorer last season has made me very proud.
“I hope that most of the City fans will understand that I have given them my all on the pitch and that my dedication to the City cause has been 100% on the pitch.
“I hope I have done my bit to help City continue their progress towards their ambition to be champions of England and to advance in the Champions League.
“I have no doubt that the players and management of City will achieve great success in the future.”