The Gunners last met Barcelona at the quarter-final stage of last season’s Champions League, with the Spanish giants getting a 6-3 aggregate victory.
“My reaction is very simple – difficult but possible,” Wenger told the club’s official website.
“I didn’t want anybody really, in that all teams would have been difficult. You could have said that Schalke – a team with less history in the Champions League – would have been easier maybe. But the advantage is that we will be on our toes and we’ll be ready.
“Revenge is not on my mind. We want to qualify and we want to knock them out. So is it difficult? Yes. Is it possible? Yes.
“Barcelona are certainly the favourites [for the competition] and a famous team but, on their side, they did not want us either because they know they will get a game.
“I think we are better than last year and we have a good opportunity to show that. I won’t come out on [how we will make it a different game]. What is on my mind right now is Stoke tomorrow more than Barcelona.
“We are in the middle of December and we play at the end of February. So there is a long way to go.
“It is too early to speak about this game concretely. You can just speak about the draw. The whole context might be completely different in two months. We don’t know what we will do and how we will feel.
“But the best way of going into that game with confidence is down to what we do from today until then. If we do well in the league, the FA Cup and the Carling Cup that will give us the best chance of knocking them out.”
