The Gunners have won only one of their last six games against Spanish clubs, losing four of them.
Atletico Madrid are without a win in their last three matches against English opponents.
In the second semi-final French giants Marseille take on Salzburg.
Marseille vs. Salzburg
Arsenal vs. Atletico Madrid
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The Portuguese legend has headed home from the World Cup in Russia but there is no doubt he made his mark.
Liverpool have unveiled their new home kit for next season, sticking with the hugely popular retro styling of the current shirt.