The Gunners won 5-0 over Porto in the second leg at the Emirates Stadium on Tuesday.
Wenger told Sky Sports: “I have a funny feeling, maybe it’s good for us to play an English team.
“We have not done well against Chelsea and not done well against Man Utd this year and it would be a good opportunity to show that we can do it against them.”
Wenger also heaped praise on Nicklas Bendtner, who scored a hat-trick against Porto.
Wenger said: “How quickly football changes. I hope that will not give him too much confidence but I am happy for him.
“He had a good game on Saturday but missed plenty of chances and three days later he has less chances and scores three goals.
“It’s good for his confidence and I hope it will give him the desire to work even harder.”