Fletcher missed most of the closing two months of last season and has yet to feature for United so far this season.
The Scottish midfielder also missed United’s pre-season trip to the United States, but has now returned to the first-team fold for the clash with Arsenal.
“Fletcher is in the squad,” said United boss Sir Alex Ferguson. “He is back now.
“He’s had a terrible time but now he’s looking terrific and he’ll be in the squad for Sunday.”